Genetics Material Test 1

Total Questions:50 Total Time: 60 Min

Remaining:

 

Questions 1 of 50

Question:Transfer of genetic information from one generation to the other is accomplished by:

Answers Choices:

DNA

Triplet codon

Transfer RNA

Messenger RNA

Questions 2 of 50

Question:Cell division requires that the genetic material be able to:

Answers Choices:

store information

be replicated

undergo rare mutations

all of these are correct

Questions 3 of 50

Question:In order to enable a chemical to serve as a genetic material, it is essential that the chemi­cal should be:

Answers Choices:

able to duplicate itself

able to form itself into a long spiral molecule

a compound of pyrimidine and purine

easily changed

Questions 4 of 50

Question:A nucleoside differs from a nucleotide in not having :

Answers Choices:

Phosphate

Sugar

Nitrogen base

Phosphate and sugar

Questions 5 of 50

Question:DNA is present in:

Answers Choices:

Nucleus only

Mitochondrion only

Chloroplast only

All of the above

Questions 6 of 50

Question:DNA strand are antiparallel because of:

Answers Choices:

H bonds

Disulphide bonds

Phosphate bonds

Phosphodiester bonds

Questions 7 of 50

Question:What is nucleotide?

Answers Choices:

Phosphoric acid

Nitrogenous base

Sugar + nitrogenous base

Sugar + nitrogenous base + phosphoric acid

Questions 8 of 50

Question:Watson and Crick got Nobel Prize for proposing DNA model in:

Answers Choices:

1959

1962

1968

1990

Questions 9 of 50

Question:Which are purines?

Answers Choices:

Adenine and guanine

Adenine and thymine

Cytosine and thymine

Cytosine and guanine

Questions 10 of 50

Question:In the carbon skeleton of the pentose sugar in DNA, what is the attachment point of a base to form a nucleoside?

Answers Choices:

\({{\rm{C}}_{\rm{3}}}\)

\({{\rm{C}}_{\rm{2}}}\)

\({{\rm{C}}_{\rm{1}}}\)

\({{\rm{C}}_{\rm{4}}}\)

Questions 11 of 50

Question:Which of the following statements regarding a double-helical molecule of DNA is true?

Answers Choices:

Each strand is identical

Each strand replicates itself

All hydroxy! groups of pentose are in­volved in linkages

Bases are perpendicular to the axis

Questions 12 of 50

Question:All the following compose nucleosides except:

Answers Choices:

purine base

pentose sugar

phosphate groups

ribose sugar

Questions 13 of 50

Question:If you grew bacteria in heavy nitrogen and then switched them to light nitrogen, how many generations after switching would have some light/light DNA?

Answers Choices:

never, because replication is semi conser­vative

the first generation

the second generation

only the third generation

Questions 14 of 50

Question:Experimental material for the study of DNA replication has been:

Answers Choices:

Drosophila melanogaster

Neurospora crassa

Pneumococcus

Escherichia coli

Questions 15 of 50

Question:Escherichia coli fully labelled with 13N is allowed to grew in 14N medium. The two strands of DNA molecule of the first generation of bacteria have:

Answers Choices:

different density and do not resemble par­ent DNA

different density but resemble parent DNA

same density and resemble parent DNA

same density but do not resemble parent DNA

Questions 16 of 50

Question:Which of the following enzymes makes short RNA chains using a DNA template?

Answers Choices:

DNA polymerase I

DNA helicase

Primase

DNA gyrase

Questions 17 of 50

Question:The enzyme which relaxes supercoiled DNA is:

Answers Choices:

Topoisomerase 1

DNA gyrase

DNA polymerase III

Primase

Questions 18 of 50

Question:In vitro synthesis of RNA and DNA was carried out first by:

Answers Choices:

Kornberg and Nirenberg

Ochoa and Kornberg

Nirenberg and Khorana

Ochoa and Nirenberg

Questions 19 of 50

Question:RNA is not found in:

Answers Choices:

Cytoplasm

Nucleus

Cell sap

Ribosomes and cytoplasm

Questions 20 of 50

Question:The diameter of Z-DNA molecule is:

Answers Choices:

18 angstron

23 Angstron

45 Angstron

34 Angstron

Questions 21 of 50

Question:A ribose nucleotide is:

Answers Choices:

Cytosine-pentose sugar-phosphate

Guanine-pentose sugar-phosphate

Uracil-pentose sugar-phosphate

Thymine-pentose sugar-phosphate

Questions 22 of 50

Question:The maximum formation of m-RNA occurs in:

Answers Choices:

cytoplasm

nucleoplasm

ribosome

centrosome

Questions 23 of 50

Question:Which of the following DNAs is transcribed on RNA template?

Answers Choices:

satellite DNA

ribosomal DNA

telomeric DNA

centromeric DNA

Questions 24 of 50

Question:Protein biosynthesis requires all the following except:

Answers Choices:

peptidyl transferase

ribosomal RNA

messenger RNA

primer protein

Questions 25 of 50

Question:Pyrimidine base present in RNA in place of thymine of DNA is:

Answers Choices:

Uracil

Adenine

Guanine

Cytosine

Questions 26 of 50

Question:RNA contains:

Answers Choices:

Glucose

Hexose

Ribose

Fructose

Questions 27 of 50

Question:DNA differs from RNA in possessing thymine in place of:

Answers Choices:

Adenine

Guanine

Cytosine

Uracil

Questions 28 of 50

Question:Because most of the amino acids are represented by more than one codon, the genetic code is:

Answers Choices:

Wobbling

Overlapping

Generate

Degenerate

Questions 29 of 50

Question:Initiation codon in eukaryotes is :

Answers Choices:

UAC

AGU

GAU

AUG

Questions 30 of 50

Question:Initiation of polypeptide chain is through:

Answers Choices:

Lysine

Leucine

Glycine

Methionine

Questions 31 of 50

Question:Protein synthesis is related to:

Answers Choices:

Mitochondrion

Ribosome

Endoplasmic reticulum

Nucleus

Questions 32 of 50

Question:Protein synthesis in an animal cell takes place:

Answers Choices:

only in the cytoplasm

in the nucleolus as well as in cytoplasm

in the cytoplasm as well as mitochondria

only on the ribosome attached to nucleon

Questions 33 of 50

Question:Anticodon loop of t-RNA contains:

Answers Choices:

3 paired bases

7 unpaired bases

5 paired bases

5 unpaired bases

Questions 34 of 50

Question:The first step in the biosynthesis of polypeptide is catalysed by:

Answers Choices:

Initiation factors (IFs)

Aminoacyl-t-RNA synthetase

Peptidyl transferase

Terminal transferase

Questions 35 of 50

Question:The enzyme aminoacyl synthetase facilitates:

Answers Choices:

joining two neighbouring amino acids on ribosomes

adoption of amino acid by a t-RNA mole­cule of its type

insertion of aminoacyl-t-RNA into the ribosome sites

transfer of aminoacyl-t-RNA from the ribosomal A-site to P-site

Questions 36 of 50

Question:Synthesis of polypeptide over m-RNA is:

Answers Choices:

Transcription

Transduction

Translation

Transformation

Questions 37 of 50

Question:The hydrolytic step leading to the release of a polypeptide chain from a ribosome is catalyzed by:

Answers Choices:

peptidyl transferase

step codons

release factors

UAA

Questions 38 of 50

Question:Given the antisense strand DNA codon 3' TAC 5', the anticodon that pairs with corresponding m-RNA codon could be:

Answers Choices:

3' CAT 5'

5' AUG 3'

5' GUA 3'

3' UAC 5'

Questions 39 of 50

Question:A potent inhibitor of protein synthesis that acts as an analogue of aminoacyl-t-RNA is:

Answers Choices:

mitomyocin

streptomycin

rifampicin

puromycin

Questions 40 of 50

Question:Which of the following is correct according to Chargaff's rules?

Answers Choices:

A + C = G + T

A + T = G + C

A + G = T + C

all the above are correct

Questions 41 of 50

Question:If one strand of DNA has the sequence CAT, GAC, TAG, what would be the base sequence in the other strand?

Answers Choices:

GTA, CTG, ATC

GAT, GTC, ACT

TAC, ACT, GCT

CAT, TAG, GAC

Questions 42 of 50

Question:Length of one loop of B-DNA:

Answers Choices:

3.4 nm

0.34 nm

10 nm

20 nm

Questions 43 of 50

Question:Genetic code translates the language of:

Answers Choices:

Proteins into that of DNA

RNA into that of DNA

RNA into that of proteins

Amino acids into that of RNA

Questions 44 of 50

Question:Transcription is the transfer of genetic information from:

Answers Choices:

chromosome to cytoplasm

t-RNA to m-RNA

DNA to m-RNA

m-RNA to r-RNA

Questions 45 of 50

Question:After initiation of transcription with core enzyme RNA polymerase the sigma factor is:

Answers Choices:

functionless

released to take part again

used during closing of chain

retained and it performs special function

Questions 46 of 50

Question:Genetic code of nuclear and mitochondrial DNA is:

Answers Choices:

similar

different

not worked out so far

DNA is not found in mitochondria

Questions 47 of 50

Question:What happened when heat killed S cells along with live R cells were injected into the mice?

Answers Choices:

Mice died and showed live R cells

Mice died and showed live S cells

Mice survived and showed live R cells

Mice survived and showed live S cells

Questions 48 of 50

Question:A mixture of heat-killed NL-cells (dead cells) and live L-cells is injected into mice. NL-type cells are pathogenic, develop a disease and kill the animals. On the other hand L-type cells are nonpathogenic. The expected results could be:

Answers Choices:

mice develop disease and die

50% mice develop disease and die

mice die without developing diseases

mice do not develop disease and also do not die

Questions 49 of 50

Question:RNA polymerase I catalyses:

Answers Choices:

tRNA synthesis

rRNA synthesis

mRNA synthesis

initiation in transcription

Questions 50 of 50

Question:Uridine monophosphate is found in:

Answers Choices:

RNA

Cell wall

DNA

Lysosome