Genetics Material Test 5

Total Questions:50 Total Time: 60 Min

Remaining:

 

Questions 1 of 50

Question:The hereditary material present in the bacterium E. coli is:

Answers Choices:

Single stranded DNA

RNA

Double stranded DNA

Protein

Questions 2 of 50

Question:Which of the following pair is correctly matched?

Answers Choices:

Frederick Griffith —discovered the phenomenon of transformation

Linus Pauling — isolated DNA for the first time

Francis Crick — proposed one gene one polypeptide hypothesis

George Beadle —proposed the concept of inborn errors

Questions 3 of 50

Question:Transformation efficiency of bacteria (as in the experiments of Avery et al.) would be drastically reduced if the transforming material is treated with:

Answers Choices:

Protease

Lipase

Deoxyribonuclease

Ribonuclease

Questions 4 of 50

Question:In DNA if 10% of guanine is present, how much thymine is present?

Answers Choices:

10%

40%

80%

20%

Questions 5 of 50

Question:Which ratio is constant for DNA?

Answers Choices:

\(\frac{{A + G}}{{T + C}}\)

\(\frac{{A + T}}{{G + C}}\)

\(\frac{{A + C}}{{U + G}}\)

\(\frac{{A + U}}{{C + G}}\)

Questions 6 of 50

Question:Which one is not true ?

Answers Choices:

A=T, G=C

A=G, T=C

C=G, T=A

G=C, A=T

Questions 7 of 50

Question:The two strands of DNA are held together by:

Answers Choices:

Peptide bonds

S—S bonds

Phosphodiester bonds

Hydrogen bonds

Questions 8 of 50

Question:Double stranded DNA virus with 20,000 base pairs has nucleotides:

Answers Choices:

10,000

20,000

40,000

666

Questions 9 of 50

Question:Hydrogen bonding in DNA occurs between the:

Answers Choices:

Bases

Ribose sugar

Deoxyribose sugar

\({\rm{P}}{{\rm{O}}_{\rm{4}}}\) molecule

Questions 10 of 50

Question:The carbon atoms of the pentose sugar involved in phosphodiester bond formation in DNA and RNA are:

Answers Choices:

\({\rm{C}}{{\rm{'}}_{\rm{1}}}\) and\({\rm{C}}{{\rm{'}}_{\rm{5}}}\)

\({\rm{C}}{{\rm{'}}_{\rm{2}}}\) and\({\rm{C}}{{\rm{'}}_{\rm{3}}}\)

\({\rm{C}}{{\rm{'}}_{\rm{3}}}\)and \({\rm{C}}{{\rm{'}}_{\rm{5}}}\)

\({\rm{C}}{{\rm{'}}_{\rm{4}}}\)and \({\rm{C}}{{\rm{'}}_{\rm{5}}}\)

Questions 11 of 50

Question:If an isolated strain of DNA is kept at 82-90\(^\circ \)C, then:

Answers Choices:

It changes into RNA

It uncoils into helices

It divides into one million pieces

No effect

Questions 12 of 50

Question:DNA replication is:

Answers Choices:

continuous and conservative

semiconservative and semidiscontinuous

conservative and semidiscontinuous

semiconservative and discontinuous

Questions 13 of 50

Question:DNA replication in eukaryotes commences:

Answers Choices:

from one end of chromosome to other

from both ends of a chromosome simulta­neously

from centromere to either end

several sites along DNA of a chromosome simultaneously

Questions 14 of 50

Question:Replication of DNA does not require:

Answers Choices:

DNA polymerase

RNA polymerase

Ligase

DNase

Questions 15 of 50

Question:'One gene one enzyme hypothesis' was proposed by:

Answers Choices:

Sutton and Boveri

Watson and Crick

Beadle and Tatum

Jacob and Monod

Questions 16 of 50

Question:A promoter site on DNA:

Answers Choices:

initiates transcription

transcribes repressor

codes for RNA polymerase

regulates termination

Questions 17 of 50

Question:DNA is.

Answers Choices:

right-handed coiling and parallel

right-handed coiling and anti-parallel

Left handed coiling and anti-parallel

Left handed coiling and parallel

Questions 18 of 50

Question:The process by which DNA of the nucleus passes genetic information to the messenger RNA is called:

Answers Choices:

Transcription

Transportation

Translation

Translocation

Questions 19 of 50

Question:Transcription involves:

Answers Choices:

protein synthesis over ribosomes

removal of wom out organelles by lyso-somes

synthesis of DNA over DNA

synthesis of RNA over DNA

Questions 20 of 50

Question:The enzyme required for transcription is:

Answers Choices:

DNA polymerase

RNA polymerase

Endonuc lease

RNase

Questions 21 of 50

Question:Adenine of transfer RNA will pair with:

Answers Choices:

Thymine

Cytosine

Uracil

Guanine

Questions 22 of 50

Question:Which site of a t-RNA molecule hydrogen bonds to a m.RNA molecule?

Answers Choices:

Codon

Anticodon

5' end of the t-RNA molecule

3'end of a t-RNA molecule

Questions 23 of 50

Question:Codon of m-RNA and anticodon of t-RNA is made of:

Answers Choices:

a set of two nitrogen bases

a set of three and two respectively

a set of three out of U, A, C and G

three and one nitrogen bases respectively

Questions 24 of 50

Question:The 'diamond code' was proposed by:

Answers Choices:

Nirenberg

George Gamow

Har Govind Khorana

J.H. Matthaei

Questions 25 of 50

Question:First deciphering of genetic code through trinucleotide synthesis was performed by:

Answers Choices:

Ochoa

Beadle and Tatum

Watson and Crick

Nirenberg

Questions 26 of 50

Question:A triplet codon means:

Answers Choices:

the presence of only three bases in m-RNA

a sequence of three nitrogen bases in r-RNA

a sequence of three nitrogen bases in m-RNA

a sequence of three nitrogen bases in t-RNA

Questions 27 of 50

Question:When more than one codon code for the same amino acid, this is called as:

Answers Choices:

redundancy of genetic code

punctuation in genetic code

continuous nature of genetic code

universal nature of genetic code

Questions 28 of 50

Question:The termination signal for protein synthesis comes from:

Answers Choices:

UAA

AUU

GUG

CTT

Questions 29 of 50

Question:Information flow of living organisms occurs in:

Answers Choices:

DNA \( \to \) RNA \( \to \) Glucose

DNA \( \to \) RNA \( \to \) Protein

RNA \( \to \) DNA \( \to \) Amino acids

Proteins \( \to \) RNA \( \to \) DNA

Questions 30 of 50

Question:Based on current knowledge which one of the following would represent the complete and accurate depiction of the "central dogma" in molecular biology?

Answers Choices:

DNA \( \to \) RNA \( \to \) DNA

DNA \( \to \) RNA \( \to \) Protein

DNA \( \to \)RNA\( \to \) Protein
       <----<------

DNA \( \to \)RNA\( \to \) Protein
   <------<-------<----------

Questions 31 of 50

Question:The "central dogma" of molecular biology:

Answers Choices:

states that DNA is template for all RNA production

states that DNA is a template only for DNA replication

states that translation precedes transcrip­tion

pertains only to prokaryotes because hu­mans are unique

Questions 32 of 50

Question:In which direction does a polypeptide chain being translated from m-RNA on a ribosome grow?

Answers Choices:

From N terminus to C terminus

From C terminus to N terminus

It depends on the protein being synthesized

It depends on the RNA being translated

Questions 33 of 50

Question:Which step of translation does not consume a high energy phosphate bond?

Answers Choices:

Translocation

Amino acid activation

Peptidyl-transferase reaction

Aminoacyl t-RNA binding to A site

Questions 34 of 50

Question:Which one of the following pairs is correctly matched?

Answers Choices:

Ribosomal RNA - Carries amino acids to the RNA site of protein synthesis

Transcription - Process by which protein is synthesized

Translation - Process by which m-RNA carries the information from nucleus to ribosomes

Anticodon - Site of t-RNA molecule hydrogen bond that binds to the m-RNA molecule

Questions 35 of 50

Question:All the following descriptions of eukaryotic RNA are true except

Answers Choices:

RNA is normally single-stranded

units of uridine equal units of adenine

it derives from antiparallel, complementary DNA

the ratio of ribose to base equals one

Questions 36 of 50

Question:A group of three nucleotides in m-RNA that specifies an amino acid is called:

Answers Choices:

Codon

Anticodon

Cistron

Transposon

Questions 37 of 50

Question:Which of the following statements is true?

Answers Choices:

The coding strand of DNA is transcribed into m-RNA

DNA ligase repairs gaps in DNA

Pyrimidines are smaller than purines

All structural genes specify the amino acid sequence of proteins

Questions 38 of 50

Question:To determine the three-dimensional structure of DNA, Watson and Crick took the help of:

Answers Choices:

Tissue culture

X-ray diffraction

Autoradiography

Electrophoresis

Questions 39 of 50

Question:The genetic transformation experiments on Diplococcus pneumoniae gave first undoubted evidence that:

Answers Choices:

DNA is made of nucleotides

DNA is the genetic material

Chromosomes are made of DNA

RNA is synthesized from DNA template

Questions 40 of 50

Question:Consider the following statements: Assertion : Amber codon is a termination codon. Reason (R): If in a m-RNA. a termination codon is present, the protein synthesis stops abruptly whether the protein synthesis is complete or not. Now select your answer from the answer code given below:

Answers Choices:

both A and R are true and R is the correct explanation of A

both A and R are true but R is not the correct explanation of A

A is true but R is false

R is true but A is false

Questions 41 of 50

Question:The eukaryotic genome differs from the prokaryotic genome because:

Answers Choices:

the DNA is circular and single stranded in prokaryotes

genes in the former case are organized into operons

the DNA is complexed with histones in prokaryotes

repetitive sequences are present in eukaryotes

Questions 42 of 50

Question:The DNA of Escherichia coli is:

Answers Choices:

double-stranded and circular

double-stranded and linear

single-stranded and linear

single-stranded and circular

Questions 43 of 50

Question:If one strand of DNA has the nucleotide sequence 5' GATCAA 3', its complementary strand will have the sequence:

Answers Choices:

5' TTGATC 3'

5' CTAGTT 3'

5' TTCATC 3'

5' TTGTTC 3'

Questions 44 of 50

Question:During S-phase:

Answers Choices:

RNA synthesis takes place

Protein synthesis takes place

DNA synthesis takes place

RNA and protein synthesis take place

Questions 45 of 50

Question:According to the Chargaff's law:

Answers Choices:

A + T = G + CD

T+A = C

A + T + G = C

\(\frac{{A + B}}{{C + T}} = 1\)

Questions 46 of 50

Question:The function of nucleolus is the synthesis of:

Answers Choices:

r-RNA

m-RNA

t-RNA

DNA

Questions 47 of 50

Question:Chargaff's rule is applicable to:

Answers Choices:

single stranded RNA

double stranded DNA

single stranded DNA

single stranded DNA and RNA

Questions 48 of 50

Question:In a DNA percentage of thymine is 20, then what is the percentage of guanine?

Answers Choices:

20

40

30

60

Questions 49 of 50

Question:The model of DNA was proposed by:

Answers Choices:

Robert Hook

Watson and Crick

Schleiden and Schwann Q

None of these