Human Genetics Test 3

Total Questions:50 Total Time: 60 Min

Remaining:

 

Questions 1 of 50

Question:An abnormality in man who are always sterile due to improper development of testis, because of an additional X-chromosome (47-XXY) is known as :

Answers Choices:

Huntington's disease

Marfan syndrome

Klinerfelters syndrome

Turner's syndrome

Questions 2 of 50

Question:Turner syndrome-a human abnormality in which the affected individuals are phenotypically females but have rudimentary sex organs and mammary glands is caused by the absence of:

Answers Choices:

One X chromosome

Y chromosome

Both X chromosomes

XY chromosomes

Questions 3 of 50

Question:The correct male human chromosome number is.

Answers Choices:

48

21 pairs of autosomes and 2 pairs of sex chromosomes

48 autosomes + one X

22 pairs of autosomes + X + Y

Questions 4 of 50

Question:A person who is trisomic for chromosome 18th pair is:

Answers Choices:

Turner's syndrome

Down's syndrome

Edward's syndrome

Cri-du-chat syndrome

Questions 5 of 50

Question:In humans, Philadelphia chromosome results from the reciprocal translocation between chromosome numbers:

Answers Choices:

3 and 11

20 and 9

10 and 20

9 and 22

Questions 6 of 50

Question:In most animals, sex of the offspring is established:

Answers Choices:

when ovum is formed

at the time of fertilization

when sex organs appear in the embryo

at birth of the child

Questions 7 of 50

Question:When released from ovary, human egg contains:

Answers Choices:

one Y chromosome

two X chromosomes

one X chromosome

XY chromosomes

Questions 8 of 50

Question:Sex of a child depends upon:

Answers Choices:

nature of sperm

nature of egg

health of father

age of mother

Questions 9 of 50

Question:Gynandromorphism in certain flies is the result of:

Answers Choices:

misdivision of chromosomes whereby one of the X-chromosomes gets lost

failure of X and Y-chromosomes to sepa­rate during gamete formation at the first zygotic division

non-disjunction of X-chromosome

repeated and sudden changes in both X and Y-chromosomes

Questions 10 of 50

Question:In human beings 45 chromosomes (44 + XO) causes:

Answers Choices:

Edward's syndrome

Turner's syndrome

Klinefelter's syndrome

Down's syndrome

Questions 11 of 50

Question:Barr body is found in:

Answers Choices:

male somatic cells

female somatic cells

sperms

ova

Questions 12 of 50

Question:Lyon's hypothesis deals with:

Answers Choices:

centromere position

genetic compatibility

genetic incompatibility

number of Barr bodies

Questions 13 of 50

Question:Women rarely experience sex-linked defects because they must be:

Answers Choices:

homozygous

carrier

heterozygous

develop immunity

Questions 14 of 50

Question:If a colour blind woman marries a normal man their children will be:

Answers Choices:

all colourblind

all normal

all daughters normal and all sons col­ourblind

all sons normal and all daughters col­ourblind

Questions 15 of 50

Question:Colour blindness is found more in males than in females because:

Answers Choices:

heterozygous females are colourblind

males having affected Y-chromosomes are colour blind

affected X-chromosome has a much higher affinity to Y-chromosome as compared to unaffected X-chromosome

the males containing the single affected X-chromosome are colour blind

Questions 16 of 50

Question:Colour blindness is inherited in:

Answers Choices:

males only

females only

both males and females

none of the above

Questions 17 of 50

Question:Haemophilia is a disease caused by the deficiency of:

Answers Choices:

RBCs

WBCs

Thromboplastin

Water in plasma

Questions 18 of 50

Question:Which is a sex-linked disease?

Answers Choices:

Haemophilia

Glaucoma

Night blindness

All of the above

Questions 19 of 50

Question:Haemophilia is most likely originated as a result of:

Answers Choices:

the crossing over of two sex chromosomes

the separation of two homologous chromosomes

a nondisjunction of chromosome number 21

a gene mutation in the X-chromosome

Questions 20 of 50

Question:It is well known that Queen Victoria of England was a carrier of gene for haemophilia. Since this is an X-linked disease, it can be predicted that:

Answers Choices:

all of her sons would have had disease

her father must definitely have had haemophilia

all of her daughters would have been carriers

haemophilia would have occurred in more of her male than her female descendants

Questions 21 of 50

Question:Genes present on Y-chromosome are called:

Answers Choices:

Basic genes

Holandric genes

Polygenic genes

Pleiotropic genes

Questions 22 of 50

Question:Joseph has hairy ears (hypertrichosis), a trait carried by a gene in his Y-chromosome. What is the chance that his grandson will inherit the trait from him?

Answers Choices:

0%

25%

50%

100%

Questions 23 of 50

Question:A man who carries a holandric gene will transmit this gene to:

Answers Choices:

1/2 his male offspring

1/2 his female offspring

all his female offspring

all his male offspring

Questions 24 of 50

Question:A man with blood group 'AB' marries a woman with 'O' blood group. In this situation:

Answers Choices:

the blood groups of their children will be the same as that of the mother

the blood group of the children differs from both the parents

while 50% of the children will have father's blood group, the remaining will have the mother's blood group

None of these

Questions 25 of 50

Question:An injured person of unknown blood group needing immediate blood transfusion can be given the following blood group:

Answers Choices:

A

O

B

AB

Questions 26 of 50

Question:What is true of blood group B?

Answers Choices:

the person can form antibody B

the person cannot form antibody B

the person cannot be given blood of O group

the person can receive blood of group AB

Questions 27 of 50

Question:The child of 'O' group has 'B' group father. The genotype of the father will be:

Answers Choices:

\({I^O}{I^O}\)

\({I^A}{I^B}\)

\({I^B}{I^B}\)

\({I^B}{I^O}\)

Questions 28 of 50

Question:What is correct for blood group O?

Answers Choices:

A antigen and b antibody

Antigen and antibody both absent

A and B antigens and a, b antibodies

No antigens but both a and b antibodies

Questions 29 of 50

Question:In wrong blood transfusion:

Answers Choices:

RBCs of recipient agglutinate

RBCs of donated blood agglutinate

WBCs of donated blood agglutinate

WBCs of recipient agglutinate

Questions 30 of 50

Question:Assertion : Person with blood group AB can take blood from any other person. Reason (R): Blood group incompatibility is due to antigen-antibody reaction. Blood group AB has no antibody and thus the antigen of other group is not affected:

Answers Choices:

Both A and R are true and R is the correct explanation of A

Both A and R are true but R is not the correct explanation of A

A is true but R is false

Both A and R are false

Questions 31 of 50

Question:Biologically marriage between which of the following is prohibited due to erythroblastosis foetalis?

Answers Choices:

\(R{h^ + }\) boy and \(R{h^ - }\) girl

\(R{h^ + }\) boy and \(R{h^ + }\) girl

\(R{h^ - }\) boy and \(R{h^ + }\) girl

\(R{h^ - }\) boy and \(R{h^ - }\) girl

Questions 32 of 50

Question:Identical twins will be produced when:

Answers Choices:

two eggs are fertilized

one spermatozoon fertilizes two ova

one ovum fertilizes two spermatozoa

one fertilized egg divides into two blasto-meres and they become separate

Questions 33 of 50

Question:Monozygotic twins are formed when:

Answers Choices:

first cleavage of zygote separates the cells

no cleavage is performed in zygote

two ova are fertilized at the same time

incomplete cleavage of zygote takes place

Questions 34 of 50

Question:In albinism, the absence of the following pigment makes the skin and hairs very light coloured:

Answers Choices:

Chlorophyll

Haemoglobin

Melanin

Carotene

Questions 35 of 50

Question:Parents are heterozygous albinos. What will be the first three children?

Answers Choices:

All heterozygous albinos

All normal

All albinos

Some normal, heterozygous and albino

Questions 36 of 50

Question:Sickle-cell anaemia is an example of:

Answers Choices:

infectious disease

deficiency disease

sex-linked inheritance

autosomal heritable disease

Questions 37 of 50

Question:The science of improving the qualities of human race by careful selection of parents is known as:

Answers Choices:

Gerontology

Euthenics

Eugenics

Genetic engineering

Questions 38 of 50

Question:Eugenics is the study of:

Answers Choices:

Evolution

Modern genetics

Development

Human genetics

Questions 39 of 50

Question:Eugenics pertains to:

Answers Choices:

study of human genetics

improvement of mankind by improving his heredity

controlling size of a human family

preserving human sperms for artificial insemination

Questions 40 of 50

Question:A child with an IQ of 140 belongs to the category:

Answers Choices:

genius

most superior

average

superior

Questions 41 of 50

Question:First protoplast fusion was done by:

Answers Choices:

Watson and Crick

Kornberg and Khorana

Jacob and Monod

Harris and Watkins

Questions 42 of 50

Question:A woman with two genes for haemophilia and a gene for colour blindness on one of the X-chromosomes marries a normal man. How will the progeny be?

Answers Choices:

All sons and daughters haemophillic and colourblind

Haemophilic and colourblind daughters

Among sons 50% haemophilic and 50% haemophilic colourblind

50% haemophilic daughter and 50% colour blind daughter

Questions 43 of 50

Question:Albinism is known to be due to an autosomal recessive mutation. The first child of a couple with normal skin pigments was an albino. What is the probability of their second child will also be an albino?

Answers Choices:

25%

50%

75%

100%

Questions 44 of 50

Question:With respect to the ABO group there found major blood types because this blood group is determined by:

Answers Choices:

three alleles all of which are recessive

three alleles of which two are codominant

three alleles of which two are recessive and the third is dominant

three alleles all of which are dominant

Questions 45 of 50

Question:Which disease is genetically linked?

Answers Choices:

Dysentery

Haemophilia

Plague

Tuberculosis

Questions 46 of 50

Question:Which theory was proposed by Bridges?

Answers Choices:

Hormonal control of sex

Development of gynandromorphs

Sex reversal

Genie balance

Questions 47 of 50

Question:During amniocentesis chromosomal abnormalities of the foetus can be detected by taking the sample of:

Answers Choices:

foetal blood

cerebrospinal fluid

mother's blood

fluid surrounding foetus

Questions 48 of 50

Question:Daughter would be colour blind only if:

Answers Choices:

only father is colour blind

only mother is colour blind

mother is carrier and father is normal

mother is carrier and father colour blind

Questions 49 of 50

Question:Construction of a recombinant DNA involves:

Answers Choices:

cleaving and rejoining DNA segments with 'endonuclease' alone

cleaving DNA segments with 'endo­nuclease' and rejoining them with 'ligase'

cleaving DNA segments with 'ligase' and rejoining them with 'endonuclease'

cleaving and rejoining DNA segments with ligase alone

Questions 50 of 50

Question:A new method of harvesting stem cells is known as:

Answers Choices:

cloning

sporogony

entrapping

schizogony